Brand Name: Nevilob 5mg Tablets
Nevilob 2.5mg Tablets
Active Ingredient: Nebivolol HCl
When is Nevilob Tablet prescribed for?
- Increased blood pressure (hypertension).
- Chronic heart failure in patient aged 70 or over.
How should you take Nevilob Tablet?
- Hypertensive patients: 1 tablet 5 mg once daily, the blood pressure lowering effect becomes evident after 1-2 weeks of treatment. Occasionally, the optimal effect is reached only after 4 weeks.
- Elderly and patients with a renal disorder: start in principle with 2.5mg daily for the treatment of increased blood pressure or 1.25 mg daily for chronic heart failure.
- Chronic heart failure: the initial up-titration should be done according to the following steps: at 1-2 weekly intervals based on patient tolerability: 1.25mg to be increased to 2.5mg once daily then to 5mg once daily and then to 10 mg once daily.
The maximum recommended dose is 10mg once daily.
When you should not take Nevilob Tablet?
1- Allergy to the drug
2- Pregnant or breast feeding
3- If the patient has one of the following disorders:
- Low blood pressure
- Serious circulation problems in the arms or legs
- Very slow heartbeat ( less than 60 beat/minute)
- Acute heart failure
- Asthma or wheezing (now or in the past)
- Untreated pheochromocytoma
- Liver function disorder
- Metabolic acidosis
Possible Drug interaction with Nevilob Tablet:
The following interactions apply to beta-adrenergic antagonists in general.
- Sedatives e.g. Barbiturates, phenothiazine, and thioridazine.
- Non-steroidal anti-inflammatory drugs (NSAID): no effect on the blood pressure lowering effect of nebivolol.
- Medicines for Psychosis & depression e.g. tricyclics, barbiturates and phenothiazines; concomitant use may enhance the hypotensive effect of the beta-blockers (additive effect).
- Medicines used for anesthesia
- Medicines for asthma or certain eye disorders such as glaucoma or dilation of the pupil.
- Medicines for treating excessive stomach acid or ulcers ( antacid drugs )
- Combinations to be used with caution: Medicines for controlling the blood pressure or for heart problems (such as amiodarone, amilodipine, clonidine, digoxin, diltiazem, felodipine, nifedipine, quinidine, verapamil, nicardipine, methyldopa, lidocaine).
- Nevilob should be taken during a meal and the antacid drug between meals.
Special Warning and Precaution when using Nevilob Tablet
Nevilob does not affect glucose levels in diabetic patients. Care should be taken in diabetic patients however, as nebivolol may mask certain symptoms of hypoglycaemia (tachycardia, palpitations).
The following warnings and precautions apply to beta-adrenergic antagonists in general:
1- Elderly patient over 65 years of age start the treatment for hypertension with 5mg once daily.
2- Patient with kidney problems start the treatment with 5mg once daily.
3- In certain situations, Nevilob should be used with greater caution. These situations are:
- Abnormally slow heartbeat
- Poor circulation in the arms or legs
- Prolonged breathing problems
- Increased production of thyroid hormone
- Psoriasis
- Allergy Nevilob may intensify the reaction to pollen or other substances are allergic to.
Possible Side Effects of Nevilob Tablet:
The adverse reactions reported, which are in most of the cases of mild to moderate intensity:
Headache – Fatigue - Dizziness - paraesthesias -Tiredness - Skin rashes-Shortness of breath – Diarrhea – constipation – nausea - Nightmares or swelling hands or feet.