Brand Name: Sycocetam 500 mg Tablet
Active Ingredient: Levetiracetam
When is Sycocetam Tablet prescribed for?
- Sycocetam is indicated as monotherapy in the treatment of partial onset seizures with or without secondary generalisation in patients from 16 years of age with newly diagnosed epilepsy.
- Sycocetam is indicated as adjunctive therapy:
- In the treatment of partial onset seizures with or without secondary generalisation in adults and children from 1 month of age with epilepsy.
- In the treatment of myoclonic seizures in adults and adolescents from 12 years of age with Juvenile Myoclonic Epilepsy.
- In the treatment of primary generalised tonic-clonic seizures in adults and adolescents from 6 years of age with Idiopathic Generalised Epilepsy.
How should you take Sycocetam Tablet?
Simple titration for monotherapy in adults:
|
|
Starting dose and first two weeks |
Increase/decrease after two weeks |
Maximum recommended dose |
|
Tablets 500 mg/scored tablets |
250 mg b.d. |
250 mg b.d. |
1500 b.d |
Simple titration for adjunctive therapy in adults:
|
|
Therapeutic starting dose |
Increase/decrease two- four weeks |
Maximum recommended dose |
|
Tablets (500 mg/scored tablets |
500 mg b.d. |
500 mg b.d. |
1500 b.d |
When Sycocetam Tablet must not be prescribed?
Hypersensitivity to the active substance or other pyrrolidone derivatives or to any of the excipients.
Possible drug interaction with Sycocetam Tablet:
No clinically significant drug-drug interacting up to date.
Some Warnings and Precautions with Sycocetam Tablet:
Pregnancy:
- There are no adequate data available from the use of levetiracetam in pregnant women. Studies in animals have shown reproductive toxicity.
- The potential risk for human is unknown.
Lactation:
- Levetiracetam is excreted in human breast milk. Therefore, breast-feeding is not recommended.
- However, if levetiracetam treatment is needed during breastfeeding, the benefit/risk of the treatment should be weighed considering the importance of breastfeeding.
Some Warnings and Precautions about Sycocetam Tablet:
• Renal insufficiency
The administration of Sycocetam to patients with renal impairment may require dose adjustment.
• Hepatic insufficiency
In patients with severely impaired hepatic function, assessment of renal function is recommended before dose selection.
Possible Side Effects with Sycocetam Tablet:
- The most commonly reported adverse reactions were somnolence, asthenia and dizziness.
- In the pooled safety analysis, there was no clear dose-response relationship but incidence and severity of the central nervous system related adverse reactions decreased over time.